PCOS Awareness Month: Backed by Science, Made for Real Life
Journal

PCOS Awareness Month: Backed by Science, Made for Real Life

04 Sep

PCOS affects more than 1 in 10 women worldwide, yet it remains one of the most under-diagnosed and under-treated conditions in women’s health. From irregular cycles and hormonal weight gain to mood instability and fertility struggles, the ripple effects of PCOS touch nearly every part of a woman’s life.

At BOND, our mission is simple: to give women daily tools that support their biology, not suppress it. This PCOS Awareness Month, we’re spotlighting the science behind one of the most promising, well-researched nutrients for women navigating PCOS-related challenges: inositol.

Clinically Studied Support for Women with PCOS

BOND’s Myo & D-Chiro Inositol blend delivers the same 40:1 ratio validated in clinical studies to support hormone balance and metabolic health.* This physiologically aligned ratio mirrors the body’s natural needs, offering targeted support for women experiencing PCOS-related symptoms.*

Clinical research has shown that inositol can help*:

  • Restore ovulation in up to 86% of women with PCOS

  • Support hormone balance by reactivating aromatase and reducing excess androgens

  • Improve insulin sensitivity and help reduce sugar cravings

  • Ease mood swings and emotional sensitivity tied to cycle phases

As highlighted in a recent review:

“Therapies based on inositols are usually well tolerated and can be extended over time without relevant side effects.”
— PMC: Intra-Ovarian Factors in PCOS, 2025


What Makes BOND Different

  • Clinically aligned 40:1 ratio of Myo & D-Chiro Inositol*

  • No added flavor, no added sugar — just pure, clean support*

  • Targets root-cause hormone dysfunction, not just surface symptoms*

  • Loved for mood, metabolism, cravings, and cycle support*

Unlike quick fixes, inositol works with your biology to help bring the body back into rhythm.*

 

Key Clinical Studies on Inositol

The science behind inositol supplementation is robust, with decades of research confirming its effectiveness in supporting metabolic, reproductive, and emotional health:

  • Gerli et al., 2007 (RCT): Myo-Inositol (4 g/day) reduced insulin, testosterone, and BMI in women with PCOS. → PubMed

  • Nordio & Proietti, 2012: The 40:1 Myo/DCI ratio outperformed Myo alone in restoring ovulation and improving metabolic markers. → PubMed

  • Palatnik et al., 2001: Myo-Inositol improved PMDD symptoms, including mood swings and irritability. → PubMed

  • Montanino Oliva et al., 2011 (Menopause Journal): In postmenopausal women, 4 g/day of Myo-Inositol improved insulin resistance, triglycerides, and blood pressure over 12 months. → Journal

  • Lentini et al., 2025 (Narrative Review): Myo supports estrogen production; DCI supports androgen modulation. The 40:1 ratio is physiologically grounded. → Dove Press

  • Gul et al., 2025 (RCT): Compared the 40:1 Inositol blend to metformin; both improved insulin sensitivity, cycle regularity, ovarian function, BMI, and quality of life. → PubMed

  • Zhang et al., 2025 (Meta-analysis): Myo-Inositol improved egg quality, MII rate, and fertilization success in IVF patients. → Frontiers

 

The Bottom Line

PCOS isn’t “just irregular cycles” — it’s a complex, full-body condition with ripple effects on energy, mood, fertility, and long-term metabolic health. The good news? Research is catching up, and women have more options than ever.

This PCOS Awareness Month, BOND is committed to shining a light on science-backed tools like inositol that help women feel more in sync with their bodies.* Because every woman deserves to feel supported — not dismissed.

 

Works Cited

 


 

 

Back to Journal
Previous post